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Tag: itraconazole

Proton Pump Inhibitors and Antifungals: How They Interfere With Absorption and Effectiveness

Proton Pump Inhibitors and Antifungals: How They Interfere With Absorption and Effectiveness

Jan, 27 2026

Proton pump inhibitors can block the absorption of key antifungals like itraconazole and ketoconazole, leading to treatment failure. Fluconazole is safer, but interactions still exist. New research shows PPIs might even boost antifungal power in some cases.

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